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Treating severe tumors by exploiting their "dependence" on iron

  Scientists at the University of California, San Francisco have successfully used an FDA-approved drug to stop the growth of tumors caused by mutations in the RAS gene, which are difficult to treat and cause about one in four cancer deaths. The  best addiction treatment center in lahore is the willing ways. The investigator used the information they discovered about cancer cells' hunger for a reactive form of iron and changed the anti-tumor drug so that it works only in these iron-made cells and allows other cells to function normally. The success, described in the 9 March 2022 issue of the Journal of Experimental Medicine, could open the door to more easily tolerated chemotherapy for many cancers that can be as difficult to treat with current methods as the disease itself. "RAS mutations alone cause more suffering than all other cancers combined and take so many lives worldwide," said the study's lead author Dr. Eric Collisson, a staff member at the UCSF Helen Dille...

How first respondent and other origin can protect their children from injury

If you are looking for the best and the superior and the best addiction treatment center in Karachi then go no further the best addiction treatment center in Karachi is the willing ways . When children witness the effects of trauma on their parents, it can change the way they see the world. Children of first respondents - police, fireman, EMTs, military, paramedics, and police officers - are especially vulnerable since, by the nature of their work, their parents are routinely exposed to traumatic events that can affect their own mental health. The best addiction treatment center in Karachi the location is here of the Karachi willing ways "In general, children who see the impact of harrowing events on their parents may become more nervous or fearful around life or feel an intense sense of duty to anticipate moods and try to keep their parents happy," says Iris Perlstein, LCADC, LPC, a clinical coordinator with First Responder Treatment Services at Penn Medicine Princeton House...

3 priorities for strengthening mental health services under COVID-19

WHO - Mental Health If you are looking for the best addiction treatment center in lahore then go no further for searching the addiction treatment center the best addiction treatment center in lahore the willing ways is the best. The theme of World Mental Health Day 2021, "Mental health care for all: let's make it a reality" is fitting in the era of COVID-19. The pandemic has not only disrupted and changed our lives, it has also exposed social and economic inequalities that have contributed significantly to the spread of the virus. These inequalities also underlie underlying health conditions that correlate with higher mortality rates in different countries.  In addition to the risk of coronavirus infection, vulnerable populations such as unemployed adults, youth, the elderly and primary care workers have increased risk of mental health symptoms and disorders. To help address this problem, World Bank Group-supported health projects in more than 100 developing countries in ...

Stigma and Abandonment of Psychiatric Treatment

  Reflections on the readiness of young doctors to face the addiction epidemic. - What is addiction? - Finding a therapist to help you get rid of addiction Key Point. - Addiction medicine is a subspecialty that focuses on the treatment of substance use disorders and should be pursued by family physicians. - Because family physicians are more likely to see addicted patients, they need to understand how to recognize the signs of addiction. - The SBIRT approach allows physicians to screen for addiction, apply simple interventions, and guide patients to treatment. Addiction medicine includes prevention, assessment, diagnosis, and treatment of addiction, as well as support for families affected by a loved one's substance use or addiction. In October 2015, the American Board of Medical Specializations (ABMS) officially recognized addiction medicine as a subspecialty. And while it's nice to have another certificate to hang on your wall or list on your resume, treating people suffering...

Addiction is an emergency: end wait times for services and expand access to life-saving medications

 The pandemic landscape has exacerbated the scope of the opioid crisis and challenged the ability of the healthcare infrastructure to respond. In 2020, more than 93,000 people died from overdoses, up 30 percent from the previous year and the highest number since the federal government declared a public health emergency in 2017. Fueled by a surge in over-the-counter opioids, particularly heroin and illicit fentanyl, 2021 is on track to be the deadliest year ever recorded for the opioid crisis in the United States. When a patient seeks help to combat their addiction, it can be a fleeting moment that has the magnitude of an emergency. A landmark 2015 study found that emergency department visits represent an opportunity to significantly improve access to buprenorphine-based treatment for opioid use disorder (OUD). Buprenorphine is a highly effective Food and Drug Administration (FDA)-approved medication that prevents craving and withdrawal symptoms and prevents relapse and overdose. Cu...

Drug addiction should be cured, not punished: an interview with Nora D. Volkow

 As part of Springer Nature's SDG3 initiative on health and wellness, we speak with Nora Volkow, Director of the National Institute on Drug Abuse at the National Institutes of Health, about her views on addiction treatment. Nora D. Volkow, M.D., is a master of the Citizen Institute on Drug Harm at the Public Institutes of Health. A psychiatry researcher and scientist, Volkow calls for a change in U.S. substance abuse policy: for those suffering from substance use disorders, it's treatment, not punishment. She argues that current laws and policies that criminalize and imprison people who use drugs are counterproductive and exacerbate the current opioid overdose crisis and other addiction-related problems. Dr. Volkow reviews his latest perspective, reported in Neuropsychopharmacology, with Elizabeth Yepez, senior publisher of Healing and Life Sciences Journals, and Rachel Daniel, co-chair of SN SDG's Mental Health Research Group and editorial director of Springer Behavioral a...

Governments liable to resist CDC project to ease access to opioid

 The federal Centers for Disease Control and Prevention (CDC) last month proposed new guidelines that would loosen restrictions on prescription opioids. However, states could respond by lifting restrictions on painkillers that have led to an epidemic of fatal overdoses nationwide.  Best addiction treatment center in Murree The proposed recommendations aim to give millions of Americans suffering from intractable and chronic pain better access to the opioid painkillers doctors say they need. The suggested guidelines also caution against using highly obsessive painkillers when none else will promote them. For the milder guidelines to have their intended effect, states would have to change or repeal existing laws that limit opioid prescriptions to three to seven days and limit the daily doses doctors can prescribe. Best addiction treatment center in Murree However, physicians and addiction experts, who typically disagree on the issue of opioid prescribing, predict that few gove...