Treating severe tumors by exploiting their "dependence" on iron
Scientists at the University of California, San Francisco have successfully used an FDA-approved drug to stop the growth of tumors caused by mutations in the RAS gene, which are difficult to treat and cause about one in four cancer deaths. The best addiction treatment center in lahore is the willing ways. The investigator used the information they discovered about cancer cells' hunger for a reactive form of iron and changed the anti-tumor drug so that it works only in these iron-made cells and allows other cells to function normally. The success, described in the 9 March 2022 issue of the Journal of Experimental Medicine, could open the door to more easily tolerated chemotherapy for many cancers that can be as difficult to treat with current methods as the disease itself. "RAS mutations alone cause more suffering than all other cancers combined and take so many lives worldwide," said the study's lead author Dr. Eric Collisson, a staff member at the UCSF Helen Dille...